Anticonvulant potential of Hydrazone derivatives: A Review

The search for antiepileptic compounds with more selective activity and lower toxicity remains an area of intensive investigation in medicinal chemistry. Hydrazone derivatives are significant because of their versatile biological actions. Hydrazone derivatives play an important role in development of various research activities such as anticonvulsant, vasodilator, antimycobacterial, antiviral, antitumoral, antimalarial, analgesic, antiinflammatory, antiplatelet, antidepressant, antimicrobial and antischistosomiasis activities. Numerous biochemical and pharmacological studies have confirmed that these molecules are effective as anticonvulsants. This review describes the Hydrazone derivatives possessing anticonvulsant activities.